Tuesday, August 25, 2020

That Feeling... free essay sample

Their jaws drop as fragments of seething perspiration slide down their necks. Their hands start to grip, torment vibrating through their bones from the quality however disregarded for what is happening before them. Tears shockingly yet obviously start to play with the edges of the man’s eyes, his girlfriend’s eyes sticking to this same pattern in the wake of taking a look at his. The air is thick with quiet brought upon by a deliberately made post-peak. Jack has shut his eyes, it is the end, and individuals wherever are left inclination, truly, lost. Be that as it may, how might they be able to not? There is nothing else to do, all things considered. Six years, six seasons, one hundred and twenty one scenes and one is left inclination achieved, cheated, exasperated, content, discouraged, puzzled, and downright there at the same time. In the event that you haven’t got on, this inclination I am talking about was brought upon millions by a show called Lost by J. We will compose a custom paper test on That Feeling or on the other hand any comparative subject explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page J. Abrams. I know since I felt it. Better put, I encountered it. Trust me, when you’re crying like an insane person and looking for the significance of â€Å"life after Lost† you realize it is an encounter and not one minute of eruption. I need to make individuals experience that snapshot of complete power. I need to have the option to take a thought regarding anything at all that I please and present it to somebody such that they won't just handle the thought, take it for what it is and proceed onward; however with the goal that they will really have picked up something and developed such that will make their lives more extravagant in even the most miniscule of ways. To have the option to affect individuals such that benefits them explicitly or society all in all is the stunning accomplishment that, after fastidiously breaking down and overanalyzing the reason for my instructive and individual excursions, I have consistently finished up I will achieve. The course to this accomplishment has consistently been the last piece in my riddle of life that I would never entirely put. My innovative undertakings had at an opportune time persuaded that by one way or another I could satisfy this objective by basically drawing something pretty or composing a charming short story that evoked a reaction from three straightforward usernames. In any case, as I developed, I understood how strangely visual I am. Seeing doesn’t consistently must accept, however it sure helps. I need to recount stories that change the world by causing individuals to develop, even only a bit. I need to do this on the most amazing visual mode of all-film. All things considered, until further notice. I have additionally revealed to myself that I can change this world through words, since I have consistently had a liking for making individuals agreeable enough with me to talk about their deepest emotions about existence and ‘the enormous picture’. Be that as it may, who knows? I don’t. I am only a youngster, all things considered. I don’t know whether I will ever illuminate the world’s most testing numerical conditions. Nor do I know whether I will ever travel to the moon. I don't have the foggiest idea whether you will ever observe me on your TV screen or rather assembling homes for the oppressed. What I can be sure of is that I will change this world. You will be influenced by me, straightforwardly or in a roundabout way. Individuals will recollect me any place I go. I will desert a heritage in this world that my extraordinary grandkids will be glad for. I will change this world, and it will be to imp rove things. Film or no film, I will leave individuals lost and found.

Saturday, August 22, 2020

Kevin Mitnick essays

Kevin Mitnick papers What lies behind the eyes of a programmer have you at any point thought about what was most important to them, what drove them to what they are today? What is a programmer? A programmer is one who breaks powerfully into a PC to recover information or find out about his casualties who have no clue their casualties YET. Be that as it may, can a programmer truly be changed to utilize his insight for good and to help fix issues with security in todays PCs. One did yet Its no different for one man a programmer from his young telephone phreaking days to what got him captured and what was done to free him. Kevin Mitnick is a programmer and this is only a little part of what his life was and what made him change to help for the great. Kevin Mitnick was conceived in 1965 and experienced childhood in San Fernando Valley, California not to a long way from Los Angeles. His dad and mom separated from when he was three years of age his mom buckled down hours as a server at a little café just to make a decent living. Kevin grew up forlorn and detached he barely ever observed his dad. What companions he had where telephone phreaks they frequently met at a little pizza parlor named Shakeys Pizza. Making sense of how to break into enormous correspondence frameworks and neighborhood PCs. The more that Kevin spent time with this children he got into telephone phreaking, increasing unlawful access to telephone utilities utilizing electronic procedures. He would invest energy in dumpsters of telephone organizations searching for old manuals that would give data about the telephone companys PCs. The first run through Kevin ever go into issue with the law was in his high schooler years he broke into his schools PC grade framewor k in which he changed no evaluations however could have. Kevin was additionally revealed that he hacked the militarys North American Air Defense Command PCs in Colorado for no particular reason. He was seventeen when he was discovered taking specialized manuals from the Pacific Bell Telephone Company the adjudicator gave him probation. He started to hack again after hello there... <!

Sunday, July 26, 2020

5 Things College Freshmen Should Know About Sexual Assault

5 Things College Freshmen Should Know About Sexual Assault February 16, 2018 PeopleImages/istock More in Relationships Violence and Abuse Spouses & Partners LGBTQ In an open letter posted online, Kenyon alumnus Michael Hayes details how Kenyon College in Gambier, Ohio mishandled the sexual assault of his sister, Chelsie. In his letter, he says that the college betrayed his trust and failed his sister when the lengthy administrative process eventually found the accused not guilty. His blunt account of what happened is not an uncommon story on college campuses. Sexual assault at U.S.  universities is a serious problem.  In fact, there is an epidemic of sexual assault with one  in five women and one in 16 men being sexually assaulted while in college, according to the National Sexual Violence Resource Center. What Should College Administrators Do Differently? Advocates say one reason the frequency of sexual assault on campuses continues to be high is that college administrators are in denial about the scope of the problem. They also point out fragmented reporting channels; long, cumbersome reporting procedures;  and the desire to maintain a certain public image as the reasons victims and their cases  are not being helped appropriately. According to  Vanessa Grigoriadis, author of  Blurred Lines: Rethinking Sex, Power Consent on Campus, 99 percent of college anti-assault orientation programs are not effective. Whats more, she says almost all American schools teach bystander education seminars which help students learn to stop assaults themselves. But the only program that is proven to work is an advanced type of womens self defense. And according to Grigoriadis, only three universities teach this type right now. These are Oregon, Ohio University, and Florida Atlantic University.   I think most Ivy League schools are doing an excellent job as well, Grigoriadis adds.  I also recently read the rules about sex put out by the University of Iowa, and I found them impressive. Christian universities have been slower to adopt many rules and protect their female students, but they are giving it a shot now. However, any school that has a major football team bringing in a ton of revenue could have some corruption within that team. Colleges need to admit to themselves that American kids form their sexual identities when they’re in college; even if that isn’t on the curriculum, that’s what a lot of students are there to do, Grigoriadis adds.  Armed with this knowledge, they should take a hard look at their party culture. They don’t need to sign up kids for orientation seminars about not raping, which is what they are doing right now. They need to address the binge drinking and out of control social life on their campuses, particularly at male-dominated frats and football parties. In her book,  Grigoriadis  says that universities also  could improve the situation by banning frat parties during the beginning weeks of college. Kids going to these parties...have just left their childhood homes, she writes. They should not be thrust into a risky party culture at the same time theyre disoriented. 5 Tips for Incoming College  Freshman Until colleges and universities realize that they need to transform the social scene on their campuses as well as improve the awareness and prevention programs, the responsibility for increasing sexual assault awareness is  going to fall on parents and students. In order to protect themselves, college freshman  need to become more aware of the risks of sexual assault as well as to learn how to protect themselves in their new and often unfamiliar environment.   Most Americans understand that acquaintance sexual assault (when an acquaintance assaults another acquaintance, such as when a boss gets handsy with an underling at a Christmas party) is much more typical than stranger sexual asssault (when a stranger breaks into someone’s apartment and rapes her), Grigoriadis explains.  But I think that in college, both genders need to understand that they are surrounded by a ton of acquaintances, and not everyone is to be trusted. Here are some additional tips that  Grigoriadis offers.   Be aware of the red zone. Sociologists who study sexual assault call the beginning of freshman year, the red zone or the riskiest part of a college womans life.  In fact,  United Educators, America’s largest collegiate insurance company, estimates that 73 percent of college sexual assault victims are freshmen or sophomores, and 88 percent of gang-rape victims are freshmen. During this period, an  unaffiliated female student (meaning a freshman before she enters a sorority) is the most at risk of all students on campus for assault. Why? She’ll be at a strange frat or a new dormitory, or she’ll be hanging out with a guy she wouldn’t invite to her room if she already had a strong clique, or she’ll be getting stinking drunk, possibly because she’s had little drinking experience in the past,  Grigoriadis explains.   All of these things put her at a very high risk for sexual assault because she is a new environment, with few if any strong contacts. Whats more,  Grigoriadis  says that new students should not be thrust into a risky party culture at a time when they are bound to be disoriented. They are signing up for classes, making new friends, learning the campus map, and letting their guard down.   Remember who your friends are. Kids today are under the illusion that the friends they have on Facebook and Snapchat are truly their friends, says  Grigoriadis. Those 500 friends are not truly their friends. And thinking that they are is dangerous. If you go to a party, and you think you’re surrounded by friends, you may be likelier to follow a guy who says he wants to get beer from his apartment back to that apartment, and before you know it, you’re in an apartment with a locked door and someone who is definitely not a true friend. Grigoriadis says the same goes for guys. They need to  realize that taking female classmates home who they feel they are friends with because they liked each others pictures on Instagram is dangerous. Girls have been speaking out loudly about how violated they feel by many of their sexual experiences in college, and you don’t want to be one of those guys who violates someone even if you didn’t mean to, Grigoriadis says.  Boys need rules for their super-casual hookups, and one of those rules should be that you don’t take home any girl who seems too drunk to consent.   Dont get involved in group chats. According to  Grigoriadis, she always advises  freshman boys to stay off of group chat with other students. They shouldn’t start group chats with guys from their dorm floor, or their pledge class, or their athletic group, she says. There is no benefit to the type of conversation guys are having with each other at 4 a.m. on group chat. At that time of night, this technology becomes a way of egging each other on to have sex. And it’s impossible to imagine that for some guys, this wont involve taking advantage of girls. Don’t forget that Brock Turner at Stanford was group-texting with his buddies from the Stanford swim team around the time he assaulted that girl behind the dumpster. Stay in a group at all times.  Grigoriadis says her number one tip for incoming freshman girls is to stay in a group.  As dumb as you may feel sticking together in a little herd walking through campus to frat parties, do that. And dont leave any freshman girl behind when you go home, she says.   She also points out that the primary risk of sexual assault is not at the actual frat party. It’s after the frat party. It’s when you go back to a guy’s off-campus apartment after the party because they ran out of beer at the party. Or even when you go back to your dorm at 2 a.m., and decide to hang out in the room of a guy you only met once before when you were getting a slice of pizza in town but who happens to live two floors down from you. You need to be very clear about why you’re in that guy’s room at 2 a.m. She stressed that just hanging out is not a clear enough reason. If you want to hook up with him, great. If you don’t want to hook up with him, go back to your room. Boundaries and good decision-making are key here. Don’t put yourself in a dangerous situation. Use yes means yes as a guideline. In the past, the rule about consensual sex was that no means no meaning that a woman had to say no in order to stop the mans behavior. But  Grigoriadis says she has found that yes means yes is a much better guideline.   That means that guys now have to explicitly ask or receive some sort of signal about whether a woman wants to have sex, she says. Silence is no longer consent. A boy could say, ‘Are you good with this?’ And the girl can answer.   Whats more, if the girl is too drunk to answer yes, then it is not consensual. Grigoriadis feels this new guideline would be extremely effective if universities adopted it.   A Word From Verywell Sexual assault on college campuses is a growing problem that parents and students need to take the time to learn more about. And because U.S. colleges and universities are still trying to catch up with the changing sexual climate, the responsibility for educating incoming freshmen about the risks of sexual assault falls on the parents and the students themselves. Whats more, parents and students need to realize that sexual assault on college campuses is different than the commonly-held view of rape. We’re not talking about a stranger hiding in the bushes outside the library. And many times we’re  not even talking about physical violence or emotionally abusive tactics, Grigoriadis explains. This is stupid, immature, and yes, criminal behavior by adolescent guys who cross the line when they think they can get away with it. The key is to make sure your college freshman not only understands that the risks  are real but also knows how to reduce the likelihood it will happen in her life.

Friday, May 22, 2020

Brain Computer Interface, Vs. Chip Technological Benefits

Brain, Brain Computer Interface, V-chip, and V-chip Technological Benefits In the movie, South Park: Bigger, Longer, and Uncut, Dr. Vosknocker implants a v-chip into Cartman’s head. The doctor then tells Cartman to say â€Å"horsefucker† in which, when Cartman complies, he is shocked. In response to the pain, he unconsciously cries out â€Å"Goddamnit† in which he is shocked as well. (Parker, Stone, Brady, 1999) In order to follow the movie’s v-chip, we would have to place the v-chip in two places. The real life v-chip would have to be placed in the right basal ganglia as well as the broca’s area in the left hemisphere. The Broca’s Area is in charge of articulation so if someone were to cuss consciously, then the v-chip would send a shock. The right basal ganglia is in charge of the automatic speech, therefore if someone were to cuss unconsciously, the v-chip would send a shock. The role of the basal ganglia is necessary for automatic speech. It lies embedded beneath the cerebral cortex, playing a role in selecting the relevant motor actions by restricting actions one would not want to perform. (Bergen, 2016) There would need to be a list of words that would be downloaded into the chip, that are banned, consequently shocking the person if the words are used. The way the V-chip would work is the chip would go into the brain, specifically near the right basal ganglia and the Broca’s area in the left hemisphere. The V-chip would have to have an external power source which would beShow MoreRelatedBionic: Artificial Pacemaker and Electronic Noses8677 Words   |  35 Pagesdevices inside the body, which are essentially enhanced to carry out certain routine tasks. These are essentially life systems that are powered by motors/actuators and sensory arrays. These send neural signals from affected part of the body to the brain, by which individual are Able to perform certain tasks independently. TABLE OF CONTENT 1. INTRODUCTION†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..2 2. TECHNOLOGIES USED†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..3 3. ARTIFICIAL MUSCLES†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..4 4. BIONIC HEART†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦4 5. BIONICRead MoreManaging Information Technology (7th Edition)239873 Words   |  960 Pages4038011—dc22 2010048598 10 9 8 7 6 5 4 3 2 1 ISBN 10: 0-13-214632-0 ISBN 13: 978-0-13-214632-6 BRIEF CONTENTS Chapter 1 Managing IT in a Digital World PART I Information Technology Chapter 2 Chapter 3 Chapter 4 1 17 Computer Systems 19 Telecommunications and Networking The Data Resource 95 60 PART II Applying Information Technology Chapter 5 Chapter 6 Chapter 7 Enterprise Systems 189 Managerial Support Systems E-Business Systems 253 187 223 PARTRead MoreDissertation Proposal on Managing Diversity of Workforce18916 Words   |  76 Pagesthe knowledge that calculates the expectations and needs of all employees into the organizational management strategy. Following the events of September 11, Business Intelligence Journal - January, 2009 Vol.2 No.1 2009 Robert D. 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It may be, however, that the consideration of the bigger, more complex picture is essential, if targeted, effective action is to be taken to address quality of working life or any of its sub-components in such a way as to produce real benefits, be they for the individual or the organisation. Quality of working life has been differentiated from the broader concept of Quality of Life. To some degree, this may be overly simplistic, as Elizur and Shye, (1990) concluded that quality of workRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesaftermath of the catastrophic war that engulfed much of the world between 1914 and 1918. Though the colonized peoples of Africa and Asia and the peasants and laborers that made up much of the world’s population in the postwar decades derived little benefit from the interwar campaigns for human rights and dignity, principles were enunciated and precedents established that would form the basis for the more broadly based human rights struggles of the last half of the century. Due in large part, howeverRead MoreStrategic Human Resource Management View.Pdf Uploaded Successfully133347 Words   |  534 Pages 607 EVOLUTION OF PRACTICES ................................... 608 SYSTEMS OF HIGH-PERFORMANCE HUMAN RESOURCE PRACTICES .......................................... 609 INDIVIDUAL BEST PRACTICES VS. SYSTEMS OF PRACTICES ........................................................... 614 UNIVERSAL PRACTICES VS. CONTINGENCY PERSPECTIVES...................................................... 616 EMPIRICAL EVIDENCE: THE CASE FOR UNIVERSAL BEST PRACTICES................................................... 618Read MoreHuman Resources Management150900 Words   |  604 PagesHR activities. Identify the three different roles of HR management. Discuss the three dimensions associated with HR management as a strategic business contributor. Explain why HR professionals and operating managers must view HR management as an interface. Discuss why ethical issues and profession alism affect HR management as a career field. ââ€"  ââ€"  ââ€"  ââ€"  ââ€"  3 HR TRANSITIONS HR Management Contributes to Organizational Success More effective management of human resources (HR) increasinglyRead MoreMarketing Mistakes and Successes175322 Words   |  702 PagesADVENTURES Chapter 2 Chapter 3 Chapter 4 Google: An Entrepreneurial Juggernaut Starbucks: A Paragon of Growth and Employee Benefits Finds Storms Boston Beer: Is Greater Growth Possible? 29 46 PART II MARKETING WARS 61 Chapter 5 Chapter 6 Chapter 7 Cola Wars: Coca-Cola vs. Pepsi PC Wars: Hewlett-Packard vs. Dell Airliner Wars: Boeing vs. Airbus; and Recent Outsourcing Woes 63 86 PART III COMEBACKS Chapter 8 Chapter 9 Chapter 10 McDonald’s: Rebirth

Friday, May 8, 2020

The Ethics of Cloning Essay - 1504 Words

According to Richard Dawkins â€Å"Cloning may be good and it may be bad. Probably its a bit of both. The question must not be greeted with reflex hysteria but decided quietly, soberly and on its own merits. We need less emotion and more thought† (Dawkins, 2011). Cloning is a general term used to describe the replication of biological material (Cloning Fact Sheet, 2009). Throughout this paper the reasoning behind why cloning is an acceptable and potentially life changing science will be examined. Along with this we will take a close look at the arguments against cloning and exploring the flaws within the argument. This will affirm that cloning is useful because it cures diseases, passes on genes, and repopulates endangered species. In†¦show more content†¦Closely related to DNA cloning is therapeutic cloning which, like DNA, is the cloning of cells; but the cloning is of embryos not in the hope to create human life but rather to harvest stem cells. The harvesting of these cells is important since these cells, unlike all of the others in the human body, are able to form into any type of cell in the body ranging from bone, tissue, blood, and brain cells. Once the human body progresses to a certain stage the stem cells change into specialized cells and from that they will only be able to form those specific cells from that point forward. The main hope from therapeutic cloning is to use these stem cells to serve as replacement cells to treat such diseases as cancer, heart disease, and even Alzheimer’s. However, one of the strongest arguments for therapeutic cloning is the use of these stem cells for organ donation (Cloning Fact Sheet, 2009). Because the cells do not require the use of immunosup pressant drugs, which is generally used when transplanting a foreign organ, with this and the fact that there is an extremely low risk of the body rejecting the organ cells since they are exact replica’s if the organ cells already existing inside the persons body (Cloning, 2011). According to one source, a long term solution to organ shortage is in fact an increased funding in therapeutic Cloning (Nelson, Rosenberg, Weiss, Goodrich, 2009). ReproductiveShow MoreRelatedThe Ethics Of Cloning894 Words   |  4 PagesPeriod 6 The ethics of cloning Early in 1997, Scottish scientist Dr. Ian Wilmot revealed to the world that he had successfully cloned an adult sheep, Dolly. With this invention, the world made a aggregate astonishment at the realization that cloning was no longer an aspect of a Science Fiction movie. Since then, human cloning has become one of the most expressing divergent topics in the world, discussions began regarding the ethic consequence of human cloning. In several recent opponentsRead MoreThe Ethics Of Human Cloning890 Words   |  4 Pages The ethics of cloning Early in 1997, Scottish scientist Dr. Ian Wilmot revealed to the world that he had successfully cloned an adult sheep, Dolly. With this invention, the world made a aggregate astonishment at the realization that cloning was no longer an aspect of a Science Fiction movie. Since then, human cloning has become one of the most expressing divergent topics in the world, discussions began regarding the ethic consequence of human cloning. In several recent opponents argue thatRead MoreThe Ethics Of Human Cloning918 Words   |  4 Pagesdebates about the ethics of in-vitro fertilization, preimplantation, stem cell research, demographic control, for example, by sterilization, genetic modification for health or physical enhancement, and human cloning. The idea of human cloning is most interesting because it is most mysterious and very complex. The topic of human cloning inclusively brings up issues also raised in the mentioned technologies. Human cloning is of two types: therapeutic and reproductive. Therapeutic cloning aims to produceRead MoreHuman Cloning Ethics1908 Words   |  8 PagesKant and Kass Tackle the Cloning Dilemma Although there are some important benefits to the use of human cloning, there are also moral challenges as well. The benefits include eradicating defective genes and infertility and a quicker recovery from traumatic injuries among other advantages. However, the disadvantages are truly thought provoking as first an individual must answer the question, â€Å"When does a human life begin?† This paper will oppose the use of human cloning on the basis that life beginsRead More The Ethics of Cloning Essay2111 Words   |  9 Pagesfreaky? Although cloning is not an important issue presently, it could potentially replace sexual reproduction as our method of producing children. Cloning is a dangerous possibility because it could lead to an over-emphasis on the importance of the genotype, no guaranteed live births, and present risks to both the cloned child and surrogate mother. It also violates the biological parent-child relationship and can cause the destruction of the normal stru cture of a family. The cloning of the deceasedRead MoreThe Ethics Of Human Cloning Essay1927 Words   |  8 Pagesis created, and this act of reproductive cloning is regarded with controversy; is it morally permissible, or is it morally grotesque. There are certain elements to consider when debating the ethics of human cloning. Leon Kass in his article â€Å"The Wisdom of Repugnance† contends that reproductive cloning is morally corrupt, describing it as offensive, repulsive, and repugnant, believing these terms to be commonly associated with regards to human cloning. Kass goes forth with his arguments byRead MoreThe Ethics Of Human Cloning2096 Words   |  9 Pagesreproductive cloning. The very prospect of cloning was introduced in the early 1900s, but only recently has made a notable impact on society. It truly is a thing of science fiction; a concept that most of society is familiar with through books and movies, but is not contemplated with much seriousness. But following the numerous successes in the cloning of animals and food that have piqued the interest of the scientific community, debates about the possibility and the ethics of human cloning have beenRead MoreThe Ethics of Cloning Essays2173 Words   |  9 Pagescould be produced (Cloning Fact Sheet, 1). This process is called cloning, and essentially it takes from one’s own genetic makeup to produce an exact replica. These exact replicas, known as clones, can benefit our society in many different ways; however, these benefits are not without great controversy and concerns. Prop onents of cloning suggest that through cloning, humans can experience a greater quality of life with fewer health concerns including hunger and reproduction. Cloning consist of threeRead MoreThe Ethics of Human Cloning Essay1294 Words   |  6 PagesHuman cloning is separated into two major categories; reproductive cloning, which uses cloning technology to create a human embryo that will produce an entire human, and therapeutic, which adopt cloning into field of medical practices to find a cure for many diseases (Kass). Reproductive cloning requires a somatic cell, a DNA-less egg, and a surrogate mother; as a result, it creates a new individual with the same genome, or genetic coding. The idea originated in Germany in 1938, but the first successfulRead MoreThe Ethics of Cloning Essay example1453 Words   |  6 PagesThe Ethics of Cloning On February 27, 1997, it was reported that scientists produced the first clone of an adult sheep, attracting international attention and raising questions on the morality of cloning. Within days, the public had called for ethics inquires and new laws banning cloning. Issues are now raised over the potentially destructive side of this scientific frontier. Many people are morally opposed to the possible consequences of women being able to give birth to themselves, or scientists

Wednesday, May 6, 2020

Afam Studies Free Essays

Michelle Fleming AFAM Ch 18 Questions 1. Explain why and how some of the New Deal programs, like the AAA and the Civilian Conservation Corps, were discriminatory. The New Deal marked an important shift in the American electoral landscape as significant numbers of African Americans gave their votes to Franklin D. We will write a custom essay sample on Afam Studies or any similar topic only for you Order Now Roosevelt and the Democratic Party for the first time, establishing a political loyalty that has endured for roughly seventy years. New Deal recovery and relief programs rapidly became a central element in blacks’ endeavors to survive the harsh economic realities of the Depression. One of these programs, the Civilian Conservation Corps, provided more than a quarter of a million young black men with jobs and was consequently another arena in which the black community waged the struggle for greater equality. Although policy prohibited discrimination, blacks and other minorities encountered numerous difficulties in the CCC. In the early years of the program, some camps were integrated. By 1935, however, there was, in the words of CCC director Fechner, a â€Å"complete segregation of colored and white enrollees,† but â€Å"segregation is not discrimination. At its peak, more than 250,000 African Americans were enrolled in nearly 150 all-black CCC company. 2. What was the effect of the Social Security Act on African Americans? How did that program reveal that whites often wanted to keep poor white women and blacks in subservient positions? The Social Security Act excluded those job categories blacks traditionally filled. â€Å"Negro Work† such as garb age collection, working in foundries, or domestic service was seen as jobs for blacks; now desperate whites used terror and intimidation of get employers to fire blacks so whites could have those jobs . How did African Americans survive the Great Depression? The depression hit African Americans hard. While many African Americans were already living in poverty, white employers felt no reservations about firing their black workers first and by 1932 more than half of African Americans were out of the jobs. Racial tensions grew as economic tensions mounted; lynching’s in the south saw a huge resurgence. â€Å"Although there were many inequities in the New Deal housing, agricultural and economic programs, blacks had opportunities to obtain employment, some in areas previously closed to them. Black writers, for example, participated in the New Deal’s writing projects, while other black Americans interviewed former slaves for the Works Project Administration (WPA)† 3. What was the NAACP role during the 1920s through the 1940s? NAACP’s anti-lynching campaign of the 1930s combined widespread publicity about the causes and costs of lynching, a successful drive to defeat Supreme Court nominee John J. Parker for his white supremacist and anti-union views and then defeat senators who voted for confirmation, and a skillful effort to lobby Congress and the Roosevelt administration to pass a federal anti-lynching law. Southern senators filibustered, but they could not prevent the formation of a national consensus against lynching; by 1938 the number of lynching’s declined steeply. Through the 1930s and much of the 1940s, the NAACP initiated suits that dismantled aspects of the edifice of segregated education, each building on the precedent of the previous one. Not until the late 1940s did the NAACP believe it politically feasible to challenge directly the constitutionality of â€Å"separate but equal† education itself. . What did the â€Å"Scottsboro Boys† case illustrate about society? What role did racism play? The case of the Scottsboro Boys shows the deep seated, racist, white fear of the alleged black male rapist, in this case in the guise of youth. It showed the power of this fear to, override evidence and reason in the determination of guilt and innocence. The issue was neither guilt nor innocence; rather, it maintained white supremacy and the repression of black freedo m. Nevertheless, the concerted efforts to undo the wrongs against the Scottsboro Boys contributed significantly to the ongoing African-American struggle and the interrelated struggle to defeat Jim Crow 5. What was the role of the Communist Party during the 1920s and 1930s. Why did some blacks find communism appealing? How did the communists affect civil rights activism? During the 1930’s, the Communist Party was heavily involved in the struggles of the people which arose during the Depression. Communists advocated for unemployment insurance, the right to organize, and for Social Security. The Communist Party attracted some blacks because it consistently renounced racism, worked on economic issues, and pursued legal equity and social justice for blacks. Ch 19 Questions 7. How did the Chicago Renaissance differ from the Harlem Renaissance? 8. How did African Americans create and employ popular culture to counteract negative stereotypes of black people? 9. How did music create a bridge between blacks and whites? 10. How did radio allow African Americans to get their music heard? 11. How did Hollywood films portray African American men and women during the 1930s and 1940s? 2. How did the images of African Americans in film and radio affect white attitudes and behavior toward blacks? 13. Why did black athletes become prominent during the 1930s and 1940s? 14. Explain what the Tuskegee Experiment was, who was responsible for the study, how did it reflect racism in America, and how did it then and now affect the attitudes of African Americans in regard to trusting the health care industry? You may need to review video clips on YouTube on this subject to gather information. Assessment How to cite Afam Studies, Essay examples

Tuesday, April 28, 2020

Introduction to Psychology Essay Example

Introduction to Psychology Essay Introduction to Psychology Introduction to the Unit Unit overview This unit focuses on understanding psychological theory and its application to life. It provides you with an understanding of: †¢ psychology as a social science †¢ the biological basis of behaviour †¢ psychological development through the lifespan †¢ sensation and perception †¢ states of consciousness †¢ memory, learning and conditioning theories †¢ cognition, language, creativity and intelligence †¢ motivation and emotion †¢ personality †¢ psychological disorders and their treatment †¢ health, stress and coping Unit objectives By the conclusion of this unit, you should be able to: †¢ demonstrate and describe the role of psychology in various areas of life †¢ demonstrate an understanding of psychology as a social science †¢ use basic terminology and concepts of psychological theory †¢ apply psychological theories to your own life Textbook The textbook for this unit is by Weiten, W. , Dunn, D. S. , Hammer, E. Y. (2012). Psychology applied to modern life: Adjustment in the 21st century (10th ed. ). Belmont, CA: Wadsworth Cengage Learning. This manual directs you to the relevant chapters of your textbook associated with each section. Unit Overview Introduction to Psychology Studying for this unit The content of this unit has been designed to maximise the learning and the integration of the subject matter. Some of the unit material may be specific to the Australian context. Students are encouraged to access additional information relevant to their local area that will assist in applying the learning. This may include specific legislation, professional associations and locally published journals. It is important that your learning is broadbased. Accessing local resources that build on what is contained in this unit will greatly assist your learning. We will write a custom essay sample on Introduction to Psychology specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Introduction to Psychology specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Introduction to Psychology specifically for you FOR ONLY $16.38 $13.9/page Hire Writer In studying this unit, you will need a notebook for completing the activities and selfassessment for each section. Within your notebook, you may like to set aside space for: †¢ completing a glossary of new terminology introduced in this unit †¢ personal notes on unit content and readings In general, students are expected to: †¢ read each section of the unit carefully and make notes on anything which is new, vague, tentative or in conflict with your knowledge or experience †¢ complete each activity fully and honestly before moving on †¢ complete readings of the textbook, making notes of important insights or facts There may be periodic suggestions or issues on which you are asked to deliberate and reflect. Sometimes these are dilemmas or difficult issues associated with the study topic. These have no obvious right or wrong answers. Activities Appropriate activities are set throughout the unit to give opportunities for further learning. They are designed to help you think through and practise the specific skills and general concepts presented in this unit. They do not need to be sent to the unit educator for marking. However, valuable learning opportunities may be missed by not completing the activities. Readings The manual directs you to readings that are found in the ‘Readings Pack’. These readings are selected from journals and books that provide additional information or a different perspective on topics covered in each section. They are from a range of authorities and expand the content of this unit. Unit Overview 2 Introduction to Psychology Self-assessment There are self-assessment questions at the end of each section to test your understanding of the section’s content. Try to recall the answers to these questions unaided. Write down what you remember, before going back to review the relevant material in the section. Some of the questions will require more than simple recall. Some will require bringing together separate issues or different pieces of information. Real learning is not just remembering what was read. It involves making this knowledge your own by: †¢ reflecting on it †¢ questioning it †¢ relating it to personal experiences †¢ restating it in your own words Assignments The assignments for this unit are carefully set so they develop from and support the key concepts and skills of the unit. Reference list The reference list for this unit is located at the end pages of the manual. Unit Overview 3 Introduction to Psychology Contents Section 1: Introduction to Psychology and the Biological Bases of Behaviour Section 2: The Science of Psychology: Tools and Research Methods Section 3: Psychological Development through the Lifespan Section 4: Personality: Theory, Research and Assessment Section 5: Sensation and Perception Section 6: Health, Stress and Coping Section 7: States of Consciousness Section 8: Memory, Learning and Conditioning Section 9: Motivation and Emotion Section 10: Cognition, Language, Creativity and Intelligence Section 11: Psychological Disorders and Social Issues Section 12: Treatment of Psychological Disorders Unit Overview 4 Introduction to Psychology Assignment requirements Ensure you keep a copy of all material submitted. This includes audio–visual recordings. Assignment Type % Word Count Week Due Academic Essay 50 2000 8 Academic Essay 50 2000 11 Unit Overview 5 Introduction to Psychology Assignment 1 Assignment Type Weighting Word Count Week Due Academic Essay 50 2000 8 Choose one of the following topics and write an essay discussing the topic in light of theory you have learned about in this unit: 1. Stress is an epidemic in the 21st century and impacts on people’s behaviour in many ways. Discuss in light of the literature. 2. Compare and contrast two theories of personality. Ensure you include a definition of personality in your essay. 3. Research suggests that first impressions are created within the first few minutes of meeting someone. Discuss the factors that impact on our perception of others and some of the elements that affect the accuracy of first impressions. Your essay should include: †¢ A clear articulation of your chosen topic †¢ A discussion of the topic as outlined in the essay descriptions above †¢ An analysis of the topic in light of current literature Unit Overview 6 Introduction to Psychology Outstanding Very good Good Satisfactory Not Satisfactory Marking Criteria – Academic Essay Content 1. Topic clearly articulated 2. Topic discussed as per essay description provided 3. Topic analysed in light of current literature 4. Evidence of familiarity with relevant literature and theory Structure 5. Appropriate introduction provided that clearly articulates the topic 6. Main ideas clearly and logically presented 7. Appropriate conclusion provided that summarises the key findings/ideas 8. Relevant literature used properly Subtotal: Yes / 85 No Partial Written Expression 9. Third person writing style used 10. Fluent writing style used with correct spelling, grammar and punctuation Presentation 11. Presentation guidelines followed as specified in the Academic Skills Guide 12. Word count within 10% of requirement Referencing 13. In-text referencing guidelines followed as specified in the Academic Skills Guide, and if not covered in the ASG then by the APA convention (6th edition) 14. List of references provided as outlined in the Academic Skills Guide, and if not covered by the ASG then by the APA convention (6th edition) Subtotal: / 15 Total Mark: /100 Weighted Scale: / 50 Grade: Unit Overview 7 Introduction to Psychology Comments: Unit Overview 8 Introduction to Psychology Assignment 2 Assignment Type Weighting Word Count Week Due Academic Essay 50 2000 11 Choose one of the areas listed below. Identify and critically evaluate the role of internal and external factors in relation to this area. 1. Sensation/Perception – e. g. physical vs. psychological 2. Motivation – e. g. intrinsic vs. extrinsic 3. Intelligence – e. g. nature vs. nurture 4. Learning – e. g. the role of external vs. internal rewards Your essay should include: †¢ A clear articulation of your chosen topic †¢ A discussion of the topic as outlined in the essay descriptions above †¢ An analysis of the topic in light of current literature Unit Overview 9 Introduction to Psychology Outstanding Very good Good Satisfactory Not Satisfactory Marking Criteria – Academic Essay Content 1. Topic clearly articulated 2. Topic discussed as per essay description provided 3. Topic analysed in light of current literature 4. Evidence of familiarity with relevant literature and theory Structure 5. Appropriate introduction provided that clearly articulates the topic 6. Main ideas clearly and logically presented 7. Appropriate conclusion provided that summarises the key findings/ideas 8. Relevant literature used properly Subtotal: Yes / 85 No Partial Written Expression 9. Third person writing style used 10. Fluent writing style used with correct spelling, grammar and punctuation Presentation 11. Presentation guidelines followed as specified in the Academic Skills Guide 12. Word count within 10% of requirement Referencing 13. In-text referencing guidelines followed as specified in the Academic Skills Guide, and if not covered in the ASG then by the APA convention (6th edition) 14. List of references provided as outlined in the Academic Skills Guide, and if not covered by the ASG then by the APA convention (6th edition) Subtotal: / 15 Total Mark: /100 Weighted Scale: / 50 Grade: Unit Overview 10 Introduction to Psychology Comments: Unit Overview 1 Introduction to Psychology Assignment support and information Important and valuable information about completing your assignments can be found in the following places: †¢ Academic skills guide – found in the ‘Student Resources’ section of my. acap †¢ Study skills guide – found in the ‘Student Resources ’ section of my. acap †¢ the ‘Learning Support’ section of the ‘Current Students’ part of the ACAP website All assignments are to be submitted online through my. acap. You can find more information on the assignment process on the ‘Assessment Information’ section of the ‘Current Students’ part of the ACAP website. Unit Overview 12

Thursday, March 19, 2020

Emphasis sponsors MCA Awards - Emphasis

Emphasis sponsors MCA Awards Emphasis sponsors MCA Awards Emphasis are proud to be sponsoring the Customer Engagement Award at the MCA Awards 2012. Last year, management consultants Navigant scooped the Customer Engagement Award for their work with Skandia investment managers. This year, the shortlist for the award comprises: Ernst Young, for their work with BMW; IBM with Nationwide; LOC Consulting with Truvo; Propaganda with Clipper Logistics; and Transform with Argos. All the companies on the shortlist have achieved great things this year and we wish them the best of luck. Well be there on the night, and Emphasis Chief Executive Rob Ashton will be presenting this years Customer Engagement Award. As well as Rob, Director Tom Wilde and Development Manager Jenny Ferguson will be attending. Please do come and say hello, whether to talk about how we can help your company or just to put names to faces. Well be reporting on the night, so its also your chance to tell us your latest news. The MCA Awards will be held on Thursday 19 April at the Hilton Hotel in Park Lane, London. For more information, and to see the companies shortlisted in other categories, click here.

Tuesday, March 3, 2020

Homemade Non-Toxic White Face Paint Recipe

Homemade Non-Toxic White Face Paint Recipe Many commercial face paints contain chemicals you dont want, such as heavy metals or allergens. Here is a recipe for a homemade white face paint you can make that uses natural, non-toxic ingredients. White Face Paint Materials You only need a few common household materials to make your own white face paint. 2 tablespoons solid white shortening5 teaspoons cornstarch1 teaspoon white flour3-5 drops glycerin Make the Face Paint Mix the cornstarch and flour together.Use a fork to blend in the shortening.Slowly mix in the glycerin until you have a creamy mixture. If the mixture is too runny, add more flour or cornstarch.You can use this white face paint as it is or you can mix in a few drops of fruit juice or food coloring to attain any color you need. Be aware, adding coloring  may result in a product which could stain your skin.Apply the face paint with a paintbrush or sponge, taking care to avoid getting it in the eyes.To remove this face paint, first use a tissue to remove as much face paint as possible. Then wash the face with soap and warm water.

Sunday, February 16, 2020

The Forest of Hands and Teeth Essay Example | Topics and Well Written Essays - 750 words

The Forest of Hands and Teeth - Essay Example The people of the village are controlled by fear of the Unconsecrated who continually try to infiltrate the village in order to satisfy their need for human flesh. The villagers live with the constant fear that the village could be breached at any time and they all would be infected which would turn the village into a world of zombies. Every day life is ruled by this fear, for instance, those villagers who were not of the Guard had to stay away from the fences in case of being bitten. Thus, it can be said that this fear was a form of social control; for, it forced the villagers to live in a certain way and adhere to certain rules. The villagers have limited options as what to do with their lives. Mary explains that â€Å"In my village an unmarried woman has three choices. She may live with her family; a man may speak for her, court her through the winter and marry her in the spring ceremonies; or she may join the Sisterhood.† The only real option the men have is to join the gu ard which patrols the fences, ensuring that no unconsecrated breach them. These options leave no room for free will and places duty above any personal wishes. These restrictions show how the villagers are obliged to live within these restrictions which tightly control their social lives. Ryan seems to be pointing at those social structures which limit our choices and free will. For instance, it is the common belief that has been passed down over generations that it is a woman’s duty to marry and have children. The Sisterhood of the village which is the religious mothers of the village so to speak also practices social control over the villagers. The Sisters believe in religious order, and tell the villagers that they are the only humans left on earth. Therefore, they are to protect their society whatever the cost, even if it means killing a loved one who has become infected. They also enforce the belief that God’s word is not to be questioned. On each door in the villa ge, a scripture is carved into the right of the door. Before, anyone is to enter or leave a building they have to place their hand on the scripture. Mary tells us that â€Å"It is our habit and duty to press a hand against these words†, demonstrating how easy it is to simply obey and get caught up in social control. The sisters have taught that this practice will protect the villagers and make God aid them. Whereas, if they do not follow these religious practices, God’s wrath would descend on the village. When Mary is forced to join the sisterhood she discovers that she has no choice but to abide by the sisters’ laws or else she would be cast out into the forest to join the ranks of the unconsecrated. Mary’s belief that there is a world beyond her village and the forest is bolstered by the arrival of the outsider, Gabrielle. Mary then realizes that the sisterhood has been keeping secrets from the villagers in order to force them to follow the edicts laid out by them. When Mary discovers that Gabrielle has become an unconsecrated, she explores the forbidden section of the Cathedral and learns that the sisters had caused Gabrielle to turn as part of an experiment. This completely shatters Mary’s belief in the sisterhood and all that they represent. The sisterhood created the Guard which Mary later finds out also kept certain secrets, such as placing stocks of food, water and weapons on the two fenced paths that lead away from

Sunday, February 2, 2020

Security after September 11 Assignment Example | Topics and Well Written Essays - 750 words

Security after September 11 - Assignment Example Also, following the Cold War with Russia, the U.S. government could conclude almost with a precision that it had contained all its enemies. However, this was far from reality as sooner than later it terrorists struck. From bombings in U.S. embassies found in East Africa to the deadly attacks at World Trade Centre and Twin Towers, it became evident that U.S. security details had to undergo considerable reforms (Bolton, 2008). In this paper, I present some of the security changes that took place following September 11 incident and their impacts on my lifestyle. Immediately after the attack, it was evident that there was a lot of security laxity at the airports. This is because the suicide bombers who hijacked the ill-fated planes successfully manoeuvred the airport security personnel to carry out the attacks. Congress responded to this by passing Aviation and Transportation Security Act, which resulted in the creation of Transportation Security Administration. Before the 9/11 incident, security issues within the airports was handled by respective airports, which also hired the services of private security companies (Pinkowski, 2008). TSA got into action almost immediately by implementing a set of procedures such as stricter guidelines on passenger and luggage screening. As at the moment, only ticketed passengers are allowed to go through security. The latest set of technologies have also been adopted at the airports to screen for weapons and any other object that could be a threat to passengers aboard the plane. Furthermore, liquids were ba nned and everybody is expected to remove their shoes while undergoing screening. Another change that happened involved tightening the immigration procedures. Unlike before the 9/11 incident, it was somehow easier for immigrants from all over the world to gain access to the United States of America. However, following the attacks, Congress responded immediately be demanding that the immigration department limit such immigration.  Ã‚  

Saturday, January 25, 2020

HPTLC Method for Determination of Edaravone

HPTLC Method for Determination of Edaravone Development and Validation of HPTLC Method for Determination of Edaravone in Bulk and in Injectable Dosage Form A simple, rapid, reliable and accurate high performance thin layer chromatography method has been developed for the estimation of Edaravone in bulk and pharmaceutical dosage form. The chromatographic development was carried out on aluminum plates, pre-coated with silica gel 60 F254, using a mixture of Toluene: Methanol (6:à ¢Ã¢â€š ¬Ã¢â‚¬ °4à ¢Ã¢â€š ¬Ã¢â‚¬ °v/v) as mobile phase. Detection was carried out densitometrically at 254à ¢Ã¢â€š ¬Ã¢â‚¬ °nm. Theà °Ã‚ Ã¢â‚¬ËœÃ¢â‚¬ ¦fvalue of analyte was found to be0.66 ±0.02. The method was validated with respect to linearity, accuracy, precision, limit of detection, limit of quantification and specificity. The linear regression analysis data for the calibration plots showed a good linear relationship with Ã… ¸2=0.9995 in the concentration range 200–600à ¢Ã¢â€š ¬Ã¢â‚¬ °ng/spot. The % assay (Mean  ± S.D.) was found to be100.27 ±0.72. Accuracy of the method was accessed by percentage recovery and found to be99.77 ±0.71%. The m ethod is new, simple and economical for routine estimation of edaravone in bulk, pre-formulation studies and pharmaceutical formulation rapidly at low cost in routine analysis. Keywords: Edaravone, HPTLC, Pharmaceutical dosage form 1. Introduction Edaravone [EDA] is a neuroprotective agent  used for the purpose of aiding  neurological  recovery  following acut ebrain ischemia and subsequent  cerebral infarction. Chemically, it is 3-Methyl-1-phenyl-2-pyrazolin-5-one. [1]. It is a strong novel free radical scavenger, was developed by Mitsubishi Tanabe Pharma Corporation (Osaka, Japan). It acts as a  potentantioxidant, protecting against  oxidative stress  and  neuronal  apoptosis Furthermore, edaravone has anti-apoptotic, anti-necrotic, and anti-inflammatory cytokine effects, as well as scavenging free radicals in cardiovascular diseases and stroke, showing protective effects in the heart, vessel, and brain in experimental studies [2-5] Different methods have been reported for the determination of EDA in the bulk drug, in the dosage forms and in biological samples. HPLC [6-7] and potentiometric titrations [8] methods are available for determination of the analyte in bulk drug and formulation. RP-HPLC [9], RP- HPTLC [10] and LC-MS/MS [11] methods are reported for determination in biological samples. The literature survey revealed that HPTLC method is not reported for determination of EDA in bulk and pharmaceutical dosage forms. The present study describes the development and validation of a simple, specific, sensitive, accurate, precise, and economical HPTLC method for determination of EDA in bulk and injectable dosage form. The proposed method is optimized and validated as per the International Conference on Harmonization (ICH) guidelines [12,13]. Fig 1: Edaravone 2. Experimental 2.1 Reagents and chemicals Edaravone was kindly gifted from Sun Pharmaceuticals, Vadodara, Gujarat, India. Edaravone injection was obtained from commercial sources within their shelf life period. All the reagents and solvents used were of analytical grade and obtained from Merck Chemicals. 2.2. Instrumentation and chromatographic conditions Chromatography was performed on 20cmÃâ€"10cm aluminum foil plates precoated with 0.2mm layers of silica gel 60 F254 (E. Merck, Germany). The plates were prewashed with methanol and water mixture, dried in the current of dry air and activated at 120 °C for 5min. Samples were applied as bands 6mm wide, by use of a CAMAG (Switzerland) Linomat 5 applicator with a CAMAG microliter syringe. A constant application rate of 150nLs−1was employed. Linear ascending development was performed in a twin-trough glass chamberwith mobile phase consisted of toluene: methanol (6:4 v/v), which gave sharp and symmetrical peak withà °Ã‚ Ã¢â‚¬ËœÃ¢â‚¬ ¦f0.66 + 0.02. The optimized chamber saturation time was 15 min at room temperature (25à ¢Ã‹â€ Ã‹Å"C ±2à ¢Ã‹â€ Ã‹Å"C) and relative humidity60% ±5%. After development, the plates were dried. Densitometric scanning, at 254 nm, was performed with a CAMAG TLC scanner 4 in absorbance mode. The source of radiation was a deuterium lamp emitting a cont inuous UV spectrum in the range of 190–400 nm. 2.3. Preparation of Standard Stock Solution An accurately weighed quantity of 10à ¢Ã¢â€š ¬Ã¢â‚¬ °mg EDA was transferred to 10à ¢Ã¢â€š ¬Ã¢â‚¬ °mL volumetric flasks, dissolved in methanol, and volume was made up to mark with the same solvent to obtain a working standard having concentration 1000à ¢Ã¢â€š ¬Ã¢â‚¬ °ngà ¢Ã¢â€š ¬Ã¢â‚¬ °ÃŽ ¼L−1. 2.4. Optimization of mobile phase Initially, different ratios of methanol and toluene were tried, but tailing of spots was observed. Finally, the mobile phasecomprising of toluene:à ¢Ã¢â€š ¬Ã¢â‚¬ °methanolà ¢Ã¢â€š ¬Ã¢â‚¬ °(6:à ¢Ã¢â€š ¬Ã¢â‚¬ °4à ¢Ã¢â€š ¬Ã¢â‚¬ °v/v) gives good resolution, sharp and symmetrical peak withà °Ã‚ Ã¢â‚¬ËœÃ¢â‚¬ ¦Ãƒ °Ã‚ Ã‚ Ã‚ ¹value of 0.63 at 254à ¢Ã¢â€š ¬Ã¢â‚¬ °nm. Figure 2: Chromatogram of standard Edaravone: (Rf = 0.63). 3. Result and discussion Validation of HPTLC method: The proposed method was validated as per the ICH guidelines in terms of its linearity, accuracy, specificity, intraday and interday precision, limit of detection (LOD), and limit of quantification (LOQ). 3.1. Linearity (Calibration Curve) The amount of standard solution equivalent to 200-600 ng/spot of EDA was spotted on the prewashed TLC plates. The plates were developed, dried and scanned as described above. The calibration plot was constructed by plotting peak areas against the corresponding concentrations (ng/spot) of EDA. The linearity of response for EDA was assessed in the concentration range 200-600 ng/spot in terms of slope, intercept and correlation coefficient values. The calibration plot showed the correlation coefficient (r2 = 0.999), the intercept (5.838) and the slope (703.3) over the concentration range of 200-600 ng/spot (Fig. 2). The results of regression analysis are shown inTable 1. 3.2 Limit of Detection (LOD) and Limit of Quantification (LOQ) The limit of detection (LOD) and the limit of quantification (LOQ) of the drug were derived by calculating the signal-to-noise ratio (S/N, i.e., 3.3 for LOD and 10 for LOQ) using the following equations designated by International Conference on Harmonization (ICH) guidelines LOD = 3.3 Ãâ€" ÏÆ'/S LOQ = 10 Ãâ€" ÏÆ'/S Where, ÏÆ' = the standard deviation of the response and S = slope of the calibration curve. 3.3 Range Suitable levels of precision and accuracy have been demonstrated between the upper and lower concentration limit of linearity under study. 3.4 Precision: The intra-day and inter-day variation for the determination of EDA was carried out at three different concentration levels 400, 600, 800 ng/spot. Intra-day variations were assessed by analyzing these concentrations in triplicate within a day and inter-day variation was assessed by using the same concentration of drug and analyzing it different days and time. Accuracy: The accuracy of the method was determined by the use of standard addition at three different levels. The pre analyzed sample solution of 400 ng/spot of EDA was spiked with extra amount equivalent to 80 %, 100 % and 120 % of the standard edaravone and the mixtures were analyzed by the proposed method. The experiment was conducted in triplicate. When these solutions were analyzed the recoveries were found to be within acceptable limits (Table 1). Specificity The mobile phase was optimized and it showed good result. There was no interference of diluents and other constituent’s in determining peak purity. This method is specific. Conclusion A new HPTLC method has been developed for the identification and quantification of EDA. Low cost, faster speed, and satisfactory precision and accuracy are the main features of this method. The method was successfully validated as per ICH guidelines and statistical analysis proves that the method is sensitive, specific, and repeatable. It can be conveniently employed for routine quality control analysis of EDA as bulk drug and in marketed injectable formulation. Acknowledgments The authors express their gratitude to Sun Pharmaceuticals Vadodara, Gujarat, India for providing a gift sample of Edaravone, the Management of Pioneer Pharmacy Degree College, Vadodara, Gujarat, India, and Anchrom Test lab Pvt. Ltd, Mumbai, Maharastra, India, for providing the necessary facilities. References Japanese Pharmacopoeial Forum, sixteenth edition, March 2012 Vol.21 (1), pp. 701-702. Doherty, Annette M, Annual Reports in Medicinal Chemistry, Volume 37, Boston: Academic Press. Watanabe T, Tanaka M, Watanabe K, Takamatsu Y, Tobe A,â€Å"Research and development of the free radical scavenger edaravone as a neuroprotectant.Yakugaku Zasshi, March 2004,124(3): 99–111. Higashi Y, Jitsuiki D, Chayama K, Yoshizumi M (January 2006). Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one), a novel free radical scavenger, for treatment of cardiovascular diseases.Recent Patents on Cardiovascular Drug Discovery1(1): 85–93. Kikuchi, K.; Miura, N.; Kawahara, K.; Murai, Y.; Morioka, M.; Lapchak, P.; Tanaka, E. Edaravone (radicut), a free radical scavenger, is a potentially useful addition to thrombolytic therapy in patients with acute ischemic stroke (review). Biomed. Rep. 2013, 1, 7–12. George Lunn Hplc Methods For Recently Approved Pharmaceuticals A John Wiley Sons, Inc., Publication; P.p 204-206. XIA Ya Jun, ZHANG Xiao Ping Determination of Edaravone Injection by HPLC: Chinese Journal of Pharmaceuticals; Chinese journal of pharmaceuticals; 34; 352-353 ZHANG Fu-Cheng, TIAN Shu -Xia, JIANG Ye Comparison Of Two Potentiometric Titration Determinations Of edaravone [j]; Chinese Journal Of Pharmaceuticals; 2005-09 WEI Min, XIAO Yi (Guangxi Liuzhou Municipal People s Hospital, Liuzhou 545001, China); Determination of the Concentration of Edaravone in Human Serum by RP-HPLC [J]; China Pharmacy; 2007-08 M. Gandhimathi, M. Saravana Kumar, R. Baghla and T. K. Ravi RP-HPTLC Method for theIn VitroEstimation of Edaravone in Human PlasmaIndian Pharmaceutical Association Convention Volume: 72Issue: 2 P.p: 276-282 GU Li-Qiang XIN Yan-Fei ZHANG Sheng WEN Lei YANG Shi-Bao, HU Xiao-ling, XUAN Yao-Xian; Determination of edaravone in plasma of Beagle dog by LC-MS/MS [A]; [C]; 2009 ICH-Guidelines Q2A, â€Å"Validation of Analytical Procedures: Definition and terminology,† (CPMP III/5626/94), Geneva, Switzerland, 1995. ICH-Guidelines Q2B, â€Å"Validation of Analytical Procedures: Methodology,† (CPMP/ICH/281/95) Geneva, Switzerland 1996.

Friday, January 17, 2020

Porter’s 5 Forces Analysis Essay

Threat of New Entrants. The average person can’t come along and start up a bank, but there are services, such as internet bill payment, on which entrepreneurs can capitalize. Banks are fearful of being squeezed out of the payments business, because it is a good source of fee-based revenue. Another trend that poses a threat is companies offering other financial services. What would it take for an insurance company to start offering mortgage and loan services? Not much. Also, when analyzing a regional bank, remember that the possibility of a mega bank entering into the market poses a real threat. Power of Suppliers. The suppliers of capital might not pose a big threat, but the threat of suppliers luring away human capital does. If a talented individual is working in a smaller regional bank, there is the chance that person will be enticed away by bigger banks, investment firms, etc. Power of Buyers. The individual doesn’t pose much of a threat to the banking industry, but one major factor affecting the power of buyers is relatively high switching costs. If a person has a mortgage, car loan, credit card, checking account and mutual funds with one particular bank, it can be extremely tough for that person to switch to another bank. In an attempt to lure in customers, banks try to lower the price of switching, but many people would still rather stick with their current bank. On the other hand, large corporate clients have banks wrapped around their little fingers. Financial institutions – by offering better exchange rates, more services, and exposure to foreign capital markets – work extremely hard to get high-margin corporate clients. Availability of Substitutes. As you can probably imagine, there are plenty of substitutes in the banking industry. Banks offer a suite of services over and above taking deposits and lending money, but whether it is insurance, mutual funds or fixed income securities, chances are there is a non-banking financial services company that can offer similar services. On the lending side of the business, banks are seeing competition rise from unconventional companies. Sony (NYSE: SNE), General Motors (NYSE:GM) and Microsoft (Nasdaq:MSFT) all offer preferred financing to customers who buy big ticket items. If car companies are offering 0% financing, why would anyone want to get a car loan from the bank and pay 5-10% interest? Competitive Rivalry. The banking industry is highly competitive. The financial services industry has been around for hundreds of years, and just about everyone who needs banking services already has them. Because of this, banks must attempt to lure clients away from competitor banks. They do this by offering lower financing, preferred rates and investment services. The banking sector is in a race to see who can offer both the best and fastest services, but this also causes banks to experience a lower ROA. They then have an incentive to take on high-risk projects. In the long run, we’re likely to see more consolidation in the banking industry. Larger banks would prefer to take over or merge with another bank rather than spend the money to market and advertise to people.

Thursday, January 9, 2020

The Purpose of the Sub-plot in Shakespeare’s Twelfth Night

Twelfth Night or What You Will is one of Shakespeare’s most famous comedies. It has been performed hundreds of times and adapted into a number of modern films. The main plot of the play follows Viola, a girl who is rescued from a shipwreck and enters into the service of the Duke Orsino disguised as a man. Rising quickly in his estimation, Viola begins delivering messages of love on his behalf to Olivia, a noble woman who has no interest in Orsino’s advances. Over the course of the play Olivia falls in love with the disguised Viola, Viola falls in love with Orsino, and Viola’s twin brother Sebastian, who supposedly died in the shipwreck, returns. Following Sebastian’s return the twins are mistaken for each other, leading to both†¦show more content†¦Therefore, both plots have symmetrical patterns with slight differences. In each plot, Olivia is the object of men’s affections and in both plots the men trying to woo her are thwarted. Salingar also argues that the sub-plot serves to amplify the main themes of the play. He asserts that the theme of misrule in the comic subplot â€Å"gives the underlying constructive principle of the whole play,† (Salingar 118) and the elements of unconscious parody in the sub-plot help to reinforce the theme of delusion and error. Misrule is common to both plots, perhaps more directly in the sub-plot and indirectly in the main plot. In the main plot the setting is fantasy-like, every day is a feast and the aristocracy enjoys freedom from the normal social constraints that characterized the period in which Shakespeare was writing. Misrule is necessary to explain a number of points in the main plot such as the sudden switch of romantic partners at the end of the play and Viola’s ability to remain undetected as a woman despite her feeble attempts at concealment. She nearly admits it to Olivia in the scene where she says, â€Å"What I am, and what I would, are as secret as maidenhead (1.5.). According to Cahill the subplot is, â€Å"historically-specific, more obviously grounded in Elizabethan social relations,† (63) thus the theme of misrule is represented in a more literal fashion. SirShow MoreRelated Conflict and Harmony in The Tempest Essay1390 Words   |  6 Pagesis one of Shakespeares best examples of how a natural harmony reveals itself through the actions of discourse and confusion.   To illustrate this idea best one must examine the historical context upon which The Tempest is based.   Because this play was published in the early 1600s, controversial cultural and political events undoubtedly surface.   Furthermore, by analyzing the sub-plots in the play, the reader has a better understanding of Shakespeares purpose for including multi-plots, which is toRead MoreWilliam Shakespeare s Twelfth Night1507 Words   |  7 Pages Twelfth Night is a dramatic comedy which revolves around the classic Shakespearean traits of comedy, which are difficult to categorise but generally identifiable in that they often contain dazzling word play, irony, and a greater emphasis on situations than characters. 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Shakespeare makes use of the many characters, and choreographs different steps and creates relationships and the plot, and sub-plot, to make Twelfth Night complete, with its many themes. One of the central messages of this play is prominently, love. With this main theme, Shakespeare creates an interesting plot and sub-plot

Wednesday, January 1, 2020

Review Of Higher Learning - 966 Words

Higher learning is a movie about 1990’s incoming freshman class at Columbus University. The class is a diverse group of Caucasian, African American, Jewish, and Hispanic people who are all trying to discover what they want and where they fit in at a university that has already categorized them and placed them in boxes based on social background. They must endure in a society full of prejudice, racism, and appropriation of rape cultural while trying to find a sense of belonging. Most of the Caucasians are blinded by the reality of black people because of their Disney World, â€Å"we are all one†, lives. Other Caucasians see black people as threats and even band together to form a white supremacy group who target students who are not Caucasian. The African Americans have to deal with prejudice and racist authorities and students in a university and world that doesn’t care to protect them. The Jews and Hispanic face a lesser yet extremely similar reality. Malik William, who is played by Omar Epps is an African American male who started off nonbiased and began associating with people of all backgrounds until his altercation with Remy, played by Michael Rapaport. Remy called him out on what he thought to be reversed racism because of the Black Panther shirt Malik was wearing. Malik felt that the issue was much greater than what Remy was leading on and confronted him about it, which sent Remy into a rage. Remy took his anger out on his Jewish roommate, which cause Malik to intervene.Show MoreRelatedArticle Review : Toddlers Infer Higher Order Relational Principles On Causal Learning1808 Words   |  8 Pages Article Review: Toddlers Infer Higher-Order Relational Principles in Causal Learning Tracy Van Lone Central Washington Universityâ€Æ' Article Review: Toddlers Infer Higher-Order Relational Principles in Causal Learning There is speculation in the scientific community that human children are born with the adaptation to â€Å"think and act like scientists and philosophers† (Blaisdell, 2015). 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